Increased superconducting transition temperature of a niobium thin film proximity coupled to gold nanoparticles using linking organic molecules

The superconducting critical temperature, T(C), of thin Nb films is significantly modified when gold nanoparticles (NPs) are chemically linked to the Nb film, with a consistent enhancement when using 3 nm long disilane linker molecules. The T(C) increases by up to 10% for certain linker length and NP size. No change is observed when the nanoparticles are physisorbed with nonlinking molecules. Electron tunneling spectra acquired on the linked NPs below T(C) typically exhibit zero-bias peaks. We attribute these results to a pairing mechanism coupling electrons in the Nb and the NPs, mediated by the organic linkers.     

Temperature dependence of the fluorescence properties of thioflavin-T in propanol, a glass-forming liquid

Steady-state and time-resolved emission techniques were employed to study the nonradiative process of Thioflavin-T (ThT) in 1-propanol as a function of temperature. We found that the nonradiative rate, k(nr), decreased by about 3 orders of magnitude when the temperature was lowered to 88 K. We found remarkably good correspondence between the temperature dependence of k(nr) of ThT and the dielectric relaxation times of the 1-propanol solvent.     

Intracellular antimicrobial photodynamic therapy: a novel technique for efficient eradication of pathogenic bacteria

The increasing resistance of bacteria to antibiotics is a serious problem, caused in part by excessive and improper use of these drugs. One alternative to traditional antibiotic therapy is photodynamic antimicrobial chemotherapy (PACT) which is based on the use of a photosensitizer (PS), activated by illumination with visible light. The poor penetration of visible light through the skin limits the application of PACT to the treatment of skin infections or the use of invasive procedures. To overcome this problem we report the exploitation of light emitted as a result of the chemiluminescent reaction of luminol to excite the PS and we call this process chemiluminescent photodynamic antimicrobial therapy (CPAT). We studied the effect of free and liposome-encapsulated PS (methylene blue or toluidine blue) on bacteria under excitation by either white external light or chemiluminescence emitted by free or liposome-enclosed luminol. PACT showed slightly better performance that CPAT for free and encapsulated PS for both types of bacteria. CPAT resulted in a three log suppression of Staphylococcus aureus and two log suppression of Escherichia coli growth. The use of CPAT may prove to be a novel and more effective form of antimicrobial therapy, particularly for internal infections not easily accessible to traditional PACT.     

Elementary building blocks of self-assembled peptide nanotubes

In the world of biology, "self-assembly" is the ability of biological entities to interact with one another to form supramolecular structures. One basic group of self-assembled structures is peptide nanotubes (PNTs). However, the self-assembly mechanism, with its special characteristics, is not yet fully understood. An exceptional quantum-confined approach is shown here for the self-assembly mechanism in bio-inspired materials. We found the elementary building block of the studied PNT, which is self-assembled from short peptides composed of two phenylalanine residues, to be 0D-quantum-confined (can be related to confinement in 3D), also called a quantum dot (QD). This elementary building block can further self-assemble to a PNT formation. It has been observed that the assembly process of dots to tubes and the disassembly process of tubes to dots are reversible. We further show that a similar dipeptide can also self-assemble to a QD-like structure, with different dimensions. The presented peptide QD structures are nanometer-sized structures, with pronounced exciton effects, which may promote the use of an entirely new kind of organic QDs.     

On the dynamics and optimization of a non-smooth bistable oscillator – Application to energy harvesting

Bistable nonlinear oscillators can transform slow sinusoidal excitations into higher frequency periodic or quasi-periodic oscillations. This behaviour can be exploited to efficiently convert mechanical oscillations into electrical power, but being nonlinear, their dynamical behaviour is relatively complicated. In order to better understand the dynamics of bistable oscillators, an approximate bilinear analytical model, which is valid for narrow potential barriers, is developed. This model is expanded to the case of wider potential with experimental verification. Indeed, the model is verified by numerical simulations and a suitable Poincaré section that the analytical model captures most of bifurcations for large amplitude vibrations and can be used to optimize the harvested power of such devices. The method of Shaw and Holmes [1] is enhanced by exploiting symmetry to obtain closed form expressions of the Poincaré section and mapping.     

From Weak to Strong Coupling in ABJM Theory

The partition function of N=6{\mathcal{N}=6} supersymmetric Chern–Simons-matter theory (known as ABJM theory) on \mathbbS³{\mathbb{S}^3} , as well as certain Wilson loop observables, are captured by a zero dimensional super-matrix model. This super–matrix model is closely related to a matrix model describing topological Chern–Simons theory on a lens space. We explore further these recent observations and extract more exact results in ABJM theory from the matrix model. In particular we calculate the planar free energy, which matches at strong coupling the classical IIA supergravity action on AdS₄×\mathbbC\mathbbP³{{\rm AdS}_4\times\mathbb{C}\mathbb{P}^3} and gives the correct N ^3/2 scaling for the number of degrees of freedom of the M2 brane theory. Furthermore we find contributions coming from world-sheet instanton corrections in \mathbbC\mathbbP³{\mathbb{C}\mathbb{P}^3} . We also calculate non-planar corrections, both to the free energy and to the Wilson loop expectation values. This matrix model appears also in the study of topological strings on a toric Calabi–Yau manifold, and an intriguing connection arises between the space of couplings of the planar ABJM theory and the moduli space of this Calabi–Yau. In particular it suggests that, in addition to the usual perturbative and strong coupling (AdS) expansions, a third natural expansion locus is the line where one of the two ’t Hooft couplings vanishes and the other is finite. This is the conifold locus of the Calabi–Yau, and leads to an expansion around topological Chern–Simons theory. We present some explicit results for the partition function and Wilson loop observables around this locus.     

Sonochemical coating of paper by microbiocidal silver nanoparticles

Colloidal silver has gained wide acceptance as an antimicrobial agent, and various substrates coated with nanosilver such as fabrics, plastics, and metal have been shown to develop antimicrobial properties. Here, a simple method to develop coating of colloidal silver on paper using ultrasonic radiation is presented, and the coatings are characterized using X-ray diffraction (XRD), high resolution scanning electron microscope (HRSEM), and thermogravimetry (TGA) measurements. Depending on the variables such as precursor concentrations and ultrasonication time, uniform coatings ranging from 90 to 150 nm in thickness have been achieved. Focused ion beam (FIB) cross section imaging measurements revealed that silver nanoparticles penetrated the paper surface to a depth of more than 1 μm, resulting in highly stable coatings. The coated paper demonstrated antibacterial activity against E. coli and S. aureus, suggesting its potential application as a food packing material for longer shelf life.     

The bactericidal activity of a deuteroporphyrin-hemin mixture on gram-positive bacteria. A microbiological and spectroscopic study

The combined antibacterial activity of various porphyrins with hemin on Gram-positive bacteria was studied. Protoporphyrin, hematoporphyrin derivative and deuteroporphyrin show only a marginal inhibitory effect in the dark. However, hemin has a strong cytotoxic effect which is independent of illumination and is equally strong in the dark. The disadvantage of hemin treatment is that it is temporary. In this study, we have demonstrated that a combination of deuteroporphyrin and hemin has a unique cytotoxic activity on Staphylococcus aureus, Streptococcus faecalis and Bacillus cereus. The effect of the combined compound is stronger than that of the separate constituents, and is as strong in the dark as in the light. Only 0.005% of the initial S. aureus population survive after a 2 h treatment. Absorption and fluorescence spectra of hemin-deuteroporphyrin mixtures in water and liposomes suggest the formation of a species with spectroscopic properties which are different from those of the two constituents.